Book a consultation

Oestrogen-only patches: what is FemSeven Mono and how do I use it?

FemSeven Mono is a hormone replacement therapy (HRT) patch that contains the hormone oestradiol. This is identical to the oestrogen that’s produced by the ovaries, and it’s absorbed into the body via a small, sticky patch.

How does FemSeven Mono work?

FemSeven Mono works by replacing the oestrogen that’s lost during the perimenopause and menopause. It’s a type of systemic HRT, which means oestrogen is released directly into the bloodstream where it can travel through the entire body. This is why it can relieve many different symptoms, including hot flushes, night sweats, brain fog, vaginal dryness, depression, anxiety and mood swings.

When and how do I use FemSeven Mono?

Your patch should be applied to clean, dry skin below the waist. You can choose to stick it to your tummy, hip, bottom or thigh – wherever suits you best. You might notice some skin irritation when you remove a patch, so it’s a good idea to vary the location rather than apply it to the same place each time. Your patch should be changed once per week, on the same day, and at roughly the same time.

Unlike some patches which also contain progesterone, FemSeven Mono is an oestrogen-only patch. This means if you still have your womb, you’ll also need to take a form of progesterone or progestogen, which is usually given as a tablet or via the Mirena coil. This is because taking oestrogen can thicken the cells in the lining of the womb, and there’s a small risk of these cells turning cancerous. Taking progesterone or progestogen protects the lining of the womb.

What doses does FemSeven Mono come in?

It’s available in three strengths: 50mcg, 75mcg and 100mcg. Most people begin on a lower dose which is then titrated according to an individuals symptoms.

What are the benefits?

FemSeven Mono patches can be a convenient way to take HRT as, unlike some other patches, they only need to be changed once per week. They’re a good alternative to gels and sprays, which need to be applied daily, and can be messy to use – especially if you need a higher dose. As well as relieving symptoms of the menopause, HRT can also reduce your future risk of osteoporosis and reduce your risk of developing cardiovascular disease.

Who is FemSeven Mono suitable for?

For most people, the benefits of HRT outweigh any risks. As the oestrogen is absorbed through the skin there’s no increased risk of blood clot or stroke, and it can also be used if you have migraines. As it’s an oestrogen-only patch, FemSeven Mono can be used as an alternative to Estraderm and Estradot patches, when they are in short supply.

Can I expect any side effects?

When you first start taking HRT you may experience some minor side effects, including breast discomfort, leg cramps and breakthrough bleeding or spotting. In most cases these settle over time, but it’s important to talk to your doctor if these persist for longer than six months. If you notice sticky marks on your skin when you change a patch, these can be removed with baby oil and a dry flannel.

RELATED HRT patches explained


NHS: hormone replacement therapy

NICE: Estradiol

Oestrogen-only patches: what is FemSeven Mono and how do I use it?

Looking for Menopause Doctor? You’re in the right place!

  1. We’ve moved to a bigger home at balance for Dr Louise Newson to host all her content.

You can browse all our evidence-based and unbiased information in the Menopause Library.