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Vaginal estrogens: what is Imvaggis and how do I use it?

Imvaggis is a small vaginal pessary used to treat symptoms of vaginal dryness caused by a drop in estrogen levels during the perimenopause and menopause.

This can lead to a range of symptoms in and around your vagina, including dryness, itching and pain during sex. It can also make you more susceptible to urinary tract infections (UTIs). As your bladder and the tube leading from it (known as your urethra) can also be affected by low estrogen, you may also experience symptoms such as urgency and occasional leaks.

How does Imvaggis work?

Imvaggis contains a type of estrogen called estriol, which is made naturally in your ovaries. By replacing the lost estrogen directly in the area that needs it most, Imvaggis helps to restore elasticity and lubrication to your vagina and surrounding tissues. This helps to relieve soreness and irritation.

When and how do I use Imvaggis?

Imvaggis pessaries are small, waxy and bullet shaped. Unlike other pessaries, Imvaggis doesn’t come with a plastic applicator and is designed to be inserted with your finger, which reduces plastic waste.

When you start using Imvaggis, you should insert one pessary every night before you go to bed. After three weeks you will only need to use Imvaggis twice per week, although your healtcare professional may recommend more frequent application if your symptoms don’t improve.

What dose is Imvaggis available in?

Each Imvaggis pessary contains 30mcg of estriol, which makes it the lowest-dose topical estrogen product available in the UK.

What are the benefits?

Imvaggis pessaries have a smooth, waxy texture which makes them easy to insert, and also adds some extra moisture to your vagina as it melts. Because they contain a lower dose of estriol, it is less likely to cause irritation, and can safely be used for a long period time.

Who is Imvaggis suitable for?

Imvaggis can be used alongside other types of HRT, and may also be suitable for those who can’t or don’t want to use HRT.

As Imvaggis is oil-based, so shouldn’t be used alongside condoms or a diaphragm as it could damage the latex.

Can I expect any side effects?

Although Imvaggis is a gentle, low-dose option, you may notice some burning or irritation when you start using it, which usually settles. You may also notice a discharge when the pessary melts.


British National Formulary (BNF): Estriol

Vaginal estrogens: what is Imvaggis and how do I use it?

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